王慧，女，中國藥科大學副教授，碩士生導師，江蘇省微生物學與免疫學會理事，江蘇省“青藍工程”優秀骨干教師，江蘇省“六大人才高峰”第八批高層次人才。2008年畢業于南京醫科大學，獲免疫學博士學位。1999年獲中山醫科大學（中山大學中山醫學院）免疫學碩士學位，1992年獲徐州醫學院臨床醫學學士學位。研究方向為生物學，目前主要從事抗腫瘤藥物的研究，尤其是多糖類和多肽類抗腫瘤藥物藥效與機制的研究。近年來先后主持或參與國家科技重大專項、國家自然科學基金、教育部基金和江蘇省科技計劃項目等。目前發表學術論文40余篇，獲得市級科技進步獎2項。長期從事本科生的《醫學微生物學與免疫學》、《微生物學與免疫學》、《免疫學技術》等課程的教學工作，教學效果優秀，發表教學論文4篇，獲得校級教學成果二等獎3項。

近三年代表性論文：

1.Mengyun Ke1, Hui Wang1, Min Zhang, Yuwei Tian, Yizhou Wang, Bing Li, Jie Yu, Jie Dou, Changlin Zhou. The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo. Biochemical Pharmacology.2014,89:119-130.

2. Yuwei Tian1, Hui Wang1, Bing Li, Mengyun Ke, Jing Wang, Jie Dou, Changlin Zhou*. The cathelicidin-BF Lys16 mutant Cbf-K16 selectively inhibits non-small cell lung cancer proliferation in vitro. Oncology reports, 2013, 30:2502-2510.

3.Hui Wang1 , Mengyun Ke1, Yuwei Tian, Jing Wang, Bing Li, Yizhou Wang, Jie Dou, Changlin Zhou*. BF-30 selectively inhibits melanoma cell proliferation via cytoplasmic membrane permeabilization and DNA-binding in vitro and in B16F10-bearing mice. European Journal of Pharmacology, 2013 (707) 1–10.

4.Qingru Hao1, Hui Wang1, Jing Wang, Jie Dou, Min Zhang, Weidong Zhou, Changlin Zhou*. Effective antimicrobial activity of Cbf-K16 and Cbf-A7A13 against NDM-1-carrying Escherichia coli by DNA binding after penetrating the cytoplasmic membrane in vitro，Journal of Peptide science，2013, 19(3):173-180.

5.Mengyu Wang 1, Hui Wang 1, Ying Tang, Di Kang, Mengyun Ke, Jie Dou, Tao Xi *, Changlin Zhou *，Effective inhibition of a Strongylocentrotus nudus eggs polysaccharide against hepatocellular carcinoma is mediated via immunoregulation in vivo. Immunology Letters, 2011; 141(1):74-82.

6.Wang H1, Wang MY1, Chen J1, Tang Y, Dou J, Yu J , Xi T *, Zhou CL *.A polysaccharide from Strongylocentrotus nudus eggs protects against myelosuppression and immunosuppression in cyclophosphamide-treated mice. Int Immunopharmacol 2011;11(11):1946-1953.）

招生方向：生物學

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